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Subscribe to this list via RSS Blog posts tagged in Alpha Lipoic Acid
b2ap3_thumbnail_Alpha-lipoic-acid.jpgWHAT IS ALPHA-LIPOIC ACID?

Alpha-lipoic acid (sometimes referred to as ALA) is a co-enzyme found in every cell of the body, and is used to turn glucose into energy. Alpha-lipoic acid also functions as a powerful antioxidant, attacking "free radicals". Free radicals are produced in the body as a byproduct of energy production, and cause harmful chemical reactions that can damage cells, organs and tissues, and make it harder for the body to fight off infections.

Alpha-lipoic acid is the only antioxidant that is both water and fat-soluble, which means it has access too all parts of our body to attack free radicals and prevent oxidative damage. Alpha-lipoic acid also helps to regenerate other powerful antioxidants and make them active again.

  • Diabetes, Pre-Diabetes and Insulin Resistance
  • Peripheral Neuropathy
  • Heavy Metal clearance
  • General Antioxidant Support
Researchers believe Alpha-lipoic acid helps improve insulin sensitivity. More simply put, Alpha-lipoic acid may make it easier for your body to use blood sugar for fuel. Alpha-lipoic acid is also used to treat the symptoms and delay progression of diabetic and alcoholic peripheral neuropathy. Studies show Alpha-lipoic acid binds with toxic metals, such as mercury, arsenic, iron, and other metals that act as free radicals. Because alpha-lipoic acid can pass easily into the brain, it may help protect the brain and nerve tissue, researchers are investigating it as a potential treatment for stroke and other brain problems involving free radical damage, such as dementia.

  • General antioxidant support: 50-400 mg per day
  • Diabetes and diabetic neuropathy: 600-800 mg per day


Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a health care provider. Side effects are generally rare and may include insomnia, fatigue, diarrhea, and skin rash.

Alpha-lipoic acid has not been studied in children, pregnant or breastfeeding women and is therefore not recommended for use in these populations.

  • If you are diabetic or have low blood sugar, as Alpha-lipoic acid many lower blood sugars further.
  • If you are an alcoholic, or have Vitamin B1 (Thiamine) deficiency, as animal studies have shown that Alpha-lipoic acid may lower Vitamin B1 levels.
  • If you are on thyroid medication, monitor thyroid levels as Alpha-lipoic acid may reduce thyroid hormone levels.
  • If you are on chemotherapy, you should check with your oncologist prior to using Alpha-lipoic acid.
  • University of Wisconsin Integrative Medicine - Supplement Samplers
  • University of Maryland Medical Center - Complementary and Alternative Medicine Guide
  • Oregon State University, Linus Pauling Institute - Micronutrient Information Center

Carin Nielsen, MD Integrative Medicine I use an Integrative/Functional Medicine approach with my patients to treat a variety of chronic medical conditions. Treating symptoms simply by prescribing medication as a “band-aid” does not address the underlying factors that contributed your problems in the first place, and is not likely to provide lasting results. My approach involves getting "under the surface” (using assessments like estrogen metabolite testing) to find and correct underlying imbalances. If you are interested in learning more or if you would like to schedule a consultation, please contact our office This email address is being protected from spambots. You need JavaScript enabled to view it. or 231-638-5585.